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I think it would depend on the depth of experience on your resume. I mean, if you have experience as a CIO and a ton of articles published in journals, then it wouldn't be necessary. On the other hand, if you are fresh out college, have only worked for a single company, then I would think it would be a positive thing to show that you are engaged in the field, and trying to expand your knowledge base. The only downside I can think of was already mentioned by Christopher Nerney; you could run into someone who is somewhat dismissive of online education. I doubt even in that case that it would cause you any difficulty.