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I don't like using canned air either because of the moisture that spits out, though I must admit that it has never actually caused a problem for me. The best thing that I have found is to use is a shop vac with airflow reversed. You don't have to worry about the moisture like you do with the canned air, and the airflow is strong without being damaging. You want to make sure the intake on the shop vac is clean, and I actually use a foam air filter from my off-road motorcycle that I found would stretch over the shop vac's intake to insure clean air. If you flip over the laptop and blow the air through the intakes, I bet that you will be surprised how much dust and gunk comes out. Do not use an air compressor. You might get away with it, but there is a good chance that you will damage your cooling fan. I've even seen fan blades broken off after someone used an air compressor. Depending on the laptop, it may be worthwhile to take the keys off for cleaning, but while that can be an easy task on some laptops, it can be a real pain on others. Just air will probably do it well enough with less effort anyway.