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The big issue with virtualization and UC is real-time communications. Since virtualization typically shares serial ports, network adapters, etc. between all the VMs on a system, it is possible to have several different servers running in different VMs contending for use of a given interface to the PBX or other communications media. The way to resolve this is to dedicate a specific Ethernet adapter, USB port or whatever interface you’re using for UC to that one VM, and use different ports for the other VMs on the system.